Tyrosols and derivatives
Medchemexpress LLC (3,4-Dimethoxyphenyl)hydrazine hydrochloride | 40119-17-3 | 204.66 | 100 MG
(3,4-Dimethoxyphenyl)hydrazine hydrochloride is a drug intermediate used for the synthesis of various active compounds.
- Used for the synthesis of various active compounds
- Purity 99.84%
- Molecular weight 204.66
- Appearance: solid
- Color: light brown to gray
Apexbio Technology LLC VX-702 479543-46-9; 745833-23-2 10mM (in 1mL DMSO)
VX-702 is a small-molecule inhibitor targeting p38 mitogen-activated protein kinase (MAPK) also known as MAPK14 It is designed to inhibit p38 MAPK thereby regulating cellular responses to cytokine signaling and various stressors VX-702 exerts its biological activity primarily through ATP-competitive inhibition In experimental models VX-702 demonstrates potent inhibition with reported IC50 values ranging from 4 to 20 nM Based on these pharmacological properties VX-702 holds research potential in the study of p38 MAPK-dependent pathways platelet storage lesions and renal excretion mechanisms
![Medchemexpress LLC 6-[(aminocarbonyl)(2,6-difluorophenyl)amino]-2-(2,4-difluorophenyl)-3-pyridinecarboxamide | 745833-23-2 | MFCD11616590 | >98.0% | 404.32 | C19H12F4N4O2 | 200 MG](https://assets.fishersci.com/TFS-Assets/CCG/product-images/5000242623.png-250.jpg)
Medchemexpress LLC 6-[(aminocarbonyl)(2,6-difluorophenyl)amino]-2-(2,4-difluorophenyl)-3-pyridinecarboxamide | 745833-23-2 | MFCD11616590 | >98.0% | 404.32 | C19H12F4N4O2 | 200 MG
VX-702 is a research-grade small-molecule inhibitor selective for p38α mitogen-activated protein kinase (MAPK). It exhibits approximately 14-fold higher potency for p38α versus p38β and has demonstrated both in vitro and in vivo activity in preclinical inflammatory models. The compound is supplied as a high-purity material suitable for biochemical, cellular, and pharmacology studies.
- Selective p38α MAPK inhibition with approximately 14-fold selectivity versus p38β.
- Potent in vitro activity with reported IC50 values in the ~4-20 nM range.
- Reduces proinflammatory cytokine production (IL-6, IL-1β, TNFα) in dose-dependent studies.
- Documented in vivo pharmacokinetics, including a reported half-life of 16-20 hours.
- Supplied at high purity (>98%).
- Soluble in DMSO at ≥42 mg/mL for assay preparation.
- Intended for research use only.
Medchemexpress LLC (3,4-Dimethoxyphenyl)hydrazine hydrochloride | 40119-17-3 | 204.66 | 5 G
(3,4-Dimethoxyphenyl)hydrazine hydrochloride serves as a drug intermediate for the synthesis of various active compounds. This chemical is suitable for research applications.
- Used as a drug intermediate
- Purity of 99.8%
- Appears as a solid
- Color is light brown to gray
Medchemexpress LLC 4-Methoxyphenethyl alcohol | 702-23-8 | 152.19 | 50 G
4-Methoxyphenethyl alcohol is an aromatic alcohol, identified as a major component of the anise-like odor produced by Amorphophallus. It inhibits protein, RNA, and DNA synthesis, demonstrating a complete bacteriostatic concentration of 4.8 mM against Escherichia coli.
- Aromatic alcohol
- Major component of anise-like odor
- Inhibits protein, RNA, and DNA synthesis
- Bacteriostatic against Escherichia coli at 4.8 mM
Medchemexpress LLC 6-(N-carbamoyl-2,6-difluoroanilino)-2-(2,4-difluorophenyl)pyridine-3-carboxamide | 745833-23-2 | MFCD11616590 | 99.7% | 404.32 g/mol | C19H12F4N4O2 | 100 MG
VX-702 is a small-molecule research inhibitor selective for the p38α isoform of mitogen-activated protein kinase (MAPK). It is used to probe MAPK signaling and inflammatory cytokine production in preclinical and cellular studies. The compound is supplied as a powder with high reported purity and documented potency against p38α.
Selleck Chemical LLC ABT 702 dihydrochloride
ABT-702 is a novel potent non-nucleoside Adenosine kinase inhibitor with an IC50 of 1 7 nM It has oral activity in animal models of pain and inflammation
Apexbio Technology LLC Verbascoside 61276-17-3 100mg
Verbascoside (CAS 61276-17-3) is a small-molecule inhibitor targeting protein kinase C (PKC) and the NF- B signaling pathway It is designed to modulate these pathways thereby regulating signal transduction and transcriptional activity in cellular responses Verbascoside exerts its biological activity primarily through the inhibition of PKC and suppression of NF- B DNA-binding activation In cell-based studies Verbascoside demonstrates inhibitory activity with an IC50 value of approximately 4 8 M in RANKL-treated RAW264 7 cells and bone marrow macrophages (BMMs) Based on these pharmacological properties Verbascoside holds research potential in the investigation of PKC/NF- B-mediated signaling osteoclastogenesis and related cell signaling mechanisms
Sigma Aldrich Fine Chemicals Biosciences Metoprolol tartrate United States Pharmacopeia (USP) Reference Standard | 56392-17-7 | MFCD00056257 | 200MG
Metoprolol tartrate United States Pharmacopeia (USP) Reference Standard | Mol Wt: 684.81 | 56392-17-7 | MFCD00056257 | 200MG
Indofine Chemical Liquiritigenin With H, 20 Mg
LIQUIRITIGENIN with HPLC, Flavonoid & Coumarins, 578-86-9, 98.5% by HPLC, 10 mg